Noopept is a recent nootropic that was first patented in Russia in 1995. Noopept has been shown to have neuro-protective qualities through the stimulation of a protein known as Nerve Growth Hormones (NGH) which plays an active role in reducing and even preventing neuronal degeneration in the hippocampus. Brain-Derived Neurotrophic Factor (BDNF) is another protein that is stimulated when Noopept is administered which takes an efficacious role in reinforcing the survival of neurons, strengthening the growth and differentiation of new neurons and synapses. Noopept stimulates the AMPA and NMDA receptors and their pathways, both of these receptors are glutamatergic receptors which play roles in memory and thought processes.
Noopept is a peptide that can be taken orally and passes readily through the Blood Brain Barrier (BBB). Noopept is of the racetam chemical class that has been shown, according to studies, to be much stronger than Piracetam. Noopept has the potential of having anxiolytic benefits through the reported stimulation of Dopamine receptors D2 and D3 as well as nicotinic ACh receptors. Noopept also has both an anti-inflammatory benefit, as well as generate antioxidant advantages.
Noopept has been shown to stimulate and promote two proteins involved in generating new neurons as well as preserving and strengthening damaged neurons in the Hippocampus. The growth of new neurons suggests that Noopept, has potentially lasting effects even after administration has been halted. Noopept stimulates the expression of NGF and BDNF in rat hippocampus (Bull Exp Biol Med. 2008 Sep;146(3):334-7).
In one study Noopept was shown that Noopept may aid in treating Parkinson’s disease by alleviating amyloid oligomeric cytotoxicity. Neuroprotective and nootropic drug noopept rescues α-synuclein amyloid cytotoxicity (J Mol Biol. 2011 Dec 16;414(5):699-712).
One paper presented that the effective dose range of Noopept in comparison to Piracetam was 1000 times lower and also that spectrum of mneumotropic activity was greater in regards to Noopept. This showed that the dipeptide Noopept was much stronger than Piracetam. The original novel nootropic and neuroprotective agent noopept (Eksp Klin Farmakol. 2002 Sep-Oct;65(5):66-72).
Noopept Dosage
The recommended noopept dosage is usually 10 to 30 mg per day, taken in three 10 mg doses, one in the morning another in the afternoon and a final dosage in the evening. It is sold in both tablet and powder form, generally of 10 mg each.
Does Noopept Work?
Noopept is a peptide that is promoted as a natural method of improving cognitive functions. There has been clinical studies to suggest Noopept may increase memory recall and retention, repair or improve neuron growth in the hippocampus, and have anti-anxiety benefits. There are still many variables though that have to be looked at with improving cognitive abilities. As a result, it is very hard to determine just how effective Noopept would be for a specific person. It all comes down to their own needs and current cognitive ability as well as lifestyle choices. Noopept
Neuro Pept® Noopept (30ct)