Alpha GPC
Alpha-GPC is a Choline supplement found naturally in the brain as well as milk. Alpha-GPC is a Parasympathomimetic drug, which stimulates the Parasympathetic Nervous System (PSNS) by means of stimulating the Acetylcholine receptors used by the PSNS. Alpha-GPC is derived through highly purified soy lecithin.
Alpha-GPC is a source of Acetylecholine and a fat-soluble nootropic of the Choline chemical class. Alpha-GPC is widely used to help and to treat Alzheimer’s, to help in the recovery of victims of a Stroke, improve the memory and overall mood of people suffering from Dementia. Alpha-GPC is used as a Nootropic supplement to help improve and increase memory and cognition.
Alpha-GPC was shown to improve the performance of animals in both active and passive conditioning tests in both young and aged animals. Molecular mechanisms mediating the effects of L-alpha-glycerylphosphorylcholine, a new cognition-enhancing drug, on behavioral and biochemical parameters in young and aged rats. Pharmacol Biochem Behav. 1992 Sep;43(1):139-51.
One study showed that Alpha-GPC may share a common mechanism with both Oxiracetam and Aniracetam in cognition stimulation through the modulation of the protein Kinase C activity in both the Cerebral Cortex and the Hippocampus. Cognition stimulating drugs modulate protein kinase C activity in cerebral cortex and hippocampus of adult rats. Life Sci. 1993;53(24):1821-32.
Another study showed when Alpha-GPC is administered 90 minutes before a resistance exercise it causes an increase in post-exercise serum growth hormone and peak bench force. The study also showed that Alpha-GPC increases power output acutely when taken 45 minutes prior to working out. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise 2008 Ziegenfuss et al; licensee BioMed Central Ltd.
Alpha-GPC Dosage
The recommended Alpha-GPC dosage ranges from 300 to 1200mg. Take Alpha-GPC with food at lunch, and again with dinner. Dosing varies due to a variety of reasons such as Age, health and other various reasons.
Does Alpha-GPC Work?
A naturally occuring phospholipid precursor and metabolite, Alpha-GPC is derived from soy lecithin. Alpha-GPC has been shown to aid to potentiate the effects of growth hormone releasing hormone (GHRH) as well as increase Human Growth Hormone (HGH) secretion in both elderly and young individuals plus patients with Senile Dementia, Alzheimer’s. Alpha-GPC has also been shown to affect various biochemical and neurotransmitter systems which have been implicated in the development of Age-related Memory Dysfunction. Alpha-GPC has also been shown to reduce the time required in recovery in comatose patients suffering from sustaining a head injury and to improve the overall memory, attention, and performance in healthy individuals. Alpha-GPC causes an increase in Acetylecholine, which is its cheif mechanism of action in the stimulation of thought and memory functionality.
There are still many variables though that have to be looked at with improving cognitive abilities with Alpha-GPC. As a result, it is very hard to determine just how effective Alpha-GPC would be for a specific person. It all comes down to their own needs and current cognitive ability as well as lifestyle choices when determining the effectiveness of Alpha-GPC.
Neuro Spark Alpha GPC